A Review of Gum Hydrocolloid Polyelectrolyte Complexes (PEC) for Biomedical Applications: Their Properties and Drug Delivery Studies

The utilization of natural gum polysaccharides as the vehicle for drug delivery systems and other biomedical applications has increased in recent decades. Their biocompatibility, biodegradability, price are much cheaper than materials. It is also renewable available massive amounts, which main reasons its use pharmaceutical applications. Gum can be easily functionalized with polymers to enhance their Various aspects gums forms polyelectrolyte complexes (PECs) discussed this review. application different mathematical models were used represent release mechanisms from PECs; these include a zero-order equation, first-order Higuchi, simplified Korsmeyer–Peppas, Peppas–Sahlin.